The role of p53 p53:A TUMOR SUPPRESSOR GENE p53:A TUMOR SUPPRESSOR GENE ?(Ill) MP53+ activated Ha-ras HUMAN TUMORS Rat embryonic fibroblasts mutant p53+ activated Ha-ras Rat embryonic CHROMOSOME 17 fibroblasts 2004 24 27 Mutant+wt p53+ 120 activated Ha-ras Rat embryonic fibroblasts Fink Nigro et al.1989 Takahashi et al.1989 MISSENSE MUTATIONSThe role of p53