Basic Changes of Neuron: (I)Acute injury Neuron necrosis (red neuron,ghost cell) Neuronophagia (Il )Simple neuronal atrophy e.g.Neuronal transsynaptic degeneration (Ill)Central chromatolysis(Disapearance of central Nissl body )and Waller degeneration (IV)Forming of inclusions e.g.Negri body (V)Abnormalities of the structural proteins e.g.neurofibrillary tangle-Alzheimer disease Lewy body formation-Parkinson disease Basic Changes of Neuron： ( I ) Acute injury Neuron necrosis (red neuron, ghost cell) Neuronophagia ( II ) Simple neuronal atrophy e.g.Neuronal transsynaptic degeneration (III) Central chromatolysis (Disapearance of central Nissl body ) and Waller degeneration (IV) Forming of inclusions e.g. Negri body (V) Abnormalities of the structural proteins e.g. neurofibrillary tangle — Alzheimer disease Lewy body formation — Parkinson disease