Capillary damage Damage to the capillary endothelium(内皮) ncrease its permeability and permits the transfer of protein into interstitial compartment ° Injury agents D Viral/bacterial agents Thermal/mechanical trauma Immune Responsible for inflammatory edema Nonpitting localized redness and tendernessCapillary Damage • Damage to the capillary endothelium(内皮) • Increase its permeability and permits the transfer of protein into interstitial compartment • Injury agents Drugs Viral/bacterial agents Thermal/mechanical trauma Immune • Responsible for inflammatory edema • Nonpitting localized redness and tenderness