Reduced plasma Osmotic pressure Albumin is the serum protein MOst responsible for the maintenance of colloid osmotic pressure (胶体渗透压) a decrease in osmotic pressure can result from increased protein loss or decreased protein synthesis Increase in capillary pressure may be due to congestive heart failureReduced Plasma Osmotic Pressure Albumin is the serum protein MOST responsible for the maintenance of colloid osmotic pressure (胶体渗透压） A decrease in osmotic pressure can result from increased protein loss or decreased protein synthesis Increase in capillary pressure may be due to congestive heart failure