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有活性。若 ARF-GDP同()结合,可 contained an analogue of gtp that cannot be 引起GDP和GTP的交换 bGTP酶激活蛋白; cCa2+- ATPase d.鸟嘌呤核苷释放蛋 白 13.用剧烈方法分离到的叶绿体是Ⅱ型叶绿3. State the conclusion that can be drawn from 体,不能() following finding a.产生O b不能合成ATP 不能产生 nadPh d不能固定CO colchicine, its microtubules depoly 14.细胞的生长和分化在本质上是不同的,生 and virtually disappear. If the colchicine is 长是细胞数量的增加、干重 then washed away, the MTs appear again, 的增加:而细胞分化则是 beginning at the centrosome and elongating a.形态结构发生变化;b.生理功能发 outward at about the rate (1 gm/min)at 生变化 which tubulin polymerizes in vitro c.生化特征发生变化;d.以上都是正 确的 15.真核生物的基因表达调控发生在四个水平 上。通过对DNA的甲基化来关闭基因的4.什么是蛋白质N-连接糖基化和0-连接糖 调控则是属于( 基化?发生在何种部位? 染色质活性水平的调控;b.转录水平 调控 c.转录后加工水平的调控:d.翻译水平 的调控。 5.过氧化物酶体是怎样进行氧浓度调节的?有 什么意义? 四、简答题(选做4题,每题5分,20分) L. How does regulated secretion differ from 五、计算与推理(第1题必做,2、3选一题, 每题5分,共10分) a human 2. Dynamic instab ility causes microtubules either chromosome spread, you observe a thick fiber to grow or to shrink rapid ly. Consider with a length of about 900 nm and an apparent individual micro-tubule that is in its shrinking diameter of 30 nm, which is expected phase. hat would happen if the solution for the solenoid structure of condensed4 有活性。若 ARF-GDP 同( )结合, 可 引起 GDP 和 GTP 的交换。 a.GTPase; b.GTP 酶激活蛋白; c.Ca2+ -ATPase d.鸟嘌呤核苷释放蛋 白。 13. 用剧烈方法分离到的叶绿体是Ⅱ型叶绿 体,不能( ) 。 a. 产生 O2 b.不能合成 ATP c. 不能产生 NADPH d.不能固定 CO2 14. 细胞的生长和分化在本质上是不同的, 生 长是细胞数量的增加、干重 的增加;而细胞分化则是: ( ) a. 形态结构发生变化; b. 生理功能发 生变化; c. 生化特征发生变化; d. 以上都是正 确的。 15. 真核生物的基因表达调控发生在四个水平 上。通过对 DNA 的甲基化来关闭基因的 调控则是属于( )。 a. 染色质活性水平的调控;b. 转录水平 调控; c. 转录后加工水平的调控;d. 翻译水平 的调控。 四、简答题(选做 4 题,每题 5 分,20 分) 1. How does regulated secretion differ from constitutive secretion? 2. Dynamic instability causes microtubules either to grow or to shrink rapidly. Consider an individual micro-tubule that is in its shrinking phase. What would happen if the solution contained an analogue of GTP that cannot be hydrolyzed? 3. State the conclusion that can be drawn from the following finding: When an animal cell is treated with colchicine, its microtubules depolymerize and virtually disappear. If the colchicine is then washed away, the MTs appear again, beginning at the centrosome and elongating outward at about the rate (1 gm/min) at which tubulin polymerizes in vitro. 4. 什么是蛋白质 N-连接糖基化和 O-连接糖 基化?发生在何种部位? 5. 过氧化物酶体是怎样进行氧浓度调节的?有 什么意义? 五、计算与推理(第 1 题必做,2、3 选一题, 每题 5 分,共 10 分) 1. In an electron micrograph of a human chromosome spread, you observe a thick fiber with a length of about 900 nm and an apparent diameter of 30 nm, which is expected for the solenoid structure of condensed
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