Relative selectivity of antagonists for adrenoceptors. Relative Receptor Affinities a Antagonists Prazosin,terazosin,doxazosin 01>02 Phenoxybenzamine 01>02 Phentolamine 01=02 Rauwolscine,yohimbine,tolazoline 02>>01 Mixed antagonists Labetalol,carvedilol B1=2301>2 βAntagonists Metoprololol,acebutolol,alprenolol, atenolol,betaxolol,celiprolol,esmolol B1>B2 Propranolol,carteolol,penbutolol,pindolol,timolol B1=B2 Butoxamine 2>1 Basic Clinical Pharmacology-10th Ed.(2007) 人凤只生公版松Relative Receptor Affinities Antagonists Prazosin, terazosin, doxazosin 1 >>>> 2 Phenoxybenzamine 1 > 2 Phentolamine 1 = 2 Rauwolscine, yohimbine, tolazoline 2 >> 1 Mixed antagonists Labetalol, carvedilol 1 = 2 ³ 1 > 2 Antagonists Metoprololol, acebutolol, alprenolol, atenolol, betaxolol, celiprolol, esmolol 1 >>> 2 Propranolol, carteolol, penbutolol, pindolol, timolol 1 = 2 Butoxamine 2 >>> 1 Relative selectivity of antagonists for adrenoceptors. Basic & Clinical Pharmacology - 10th Ed. (2007)