By using multimedia teaching method,off-line,on-line method,student-centered method and otherdiversified teaching methods,we inspire students to"leam with questions"and cultivate students'critical thinking ability. 5.Teaching Evaluation Questions: 1.How many typescan adrenergic receptors be classified? 2.What different functions are there between al-R and a2-R? 3.What is the pharmacologicalmechanism of cardiovascular application of sympathomimetic drugs? 4.Why is Adrenaline used in the treatment ofanaphylactic shock and should be first choice? Chapter10 Adrenoceptor Antagonist Drugs 1.Teaching Objectives To learn the pharmacologicalactions,mechanisms and therapeutic applicationsof alpha and beta adrenergic antagonists. 2.Teaching main and difficult points (1)The action and clinical use of phentolamine. (2)The adverse effects ofa-adrenergic blockers. (3)The pharmacologicalaction and clinical use of B-R blockers ISA. (4)The pharmacologicalaction ofal receptor blockers. 3.Course Contents 3.I Classification ofadrenoceptorantagonist drugs. 3.2 Pharmacologicaleffectsand therapeutic applications of a-adrenoceptor blockers(including phentolamine,tolazoline,phenoxybenzamine,prazosin). 3.3 Classification of B-adrenoceptor blockers. 3.4 Pharmacologicaleffectsand therapeutic applications of B-adrenoceptor blockers.By using multimedia teaching method, off-line, on-line method, student-centered method and other diversified teaching methods, we inspire students to “learn with questions” and cultivate students’ critical thinking ability. 5.Teaching Evaluation Questions： 1.How many types can adrenergic receptors be classified? 2.What different functions are there between α1–R and α2–R? 3.What is the pharmacological mechanism of cardiovascular application of sympathomimetic drugs? 4.Why is Adrenaline used in the treatment of anaphylactic shock and should be first choice? Chapter10 Adrenoceptor Antagonist Drugs 1.Teaching Objectives To learn the pharmacological actions, mechanisms and therapeutic applications of alpha and beta adrenergic antagonists. 2.Teaching main and difficult points (1) The action and clinical use of phentolamine. (2) The adverse effects of α-adrenergic blockers. (3) The pharmacological action and clinical use of β-R blockers ISA. (4) The pharmacological action of α1 receptor blockers. 3. Course Contents 3.1 Classification of adrenoceptor antagonist drugs. 3.2 Pharmacological effects and therapeutic applications of α-adrenoceptor blockers (including phentolamine, tolazoline, phenoxybenzamine, prazosin). 3.3 Classification of β-adrenoceptor blockers. 3.4 Pharmacological effects and therapeutic applications of β-adrenoceptor blockers