3.5 Features of selective BI receptor blockers and B-adrenergic blockers with ISA. 4.Teaching Methods By using multimedia teaching method,off-line,on-line method,student-centered method and otherdiversified teaching methods,we inspire students to"leam with questions"and cultivate students'critical thinking ability. 5.Teaching Evaluation Questions: 1.Why can phentolamine not be used in constitutionalhypertension? 2.Can B-adrenergic blockers be used forheart failure clinically? 3.What are effects ofrennin angiotensin system on the blood pressure? Chapter11 Introduction to the Pharmacology of CNS Drugs 1.Teaching Objectives 1.1 To leam methods for the Study ofCNS Pharmacology. 1.2 To learn ion Channels Neurotransmitter Receptors. 1.3 To learn central Neurotransmitters. 1.4 To learn sites of Drug Action. 1.5 To understand identification ofCentral Neurotransmitters. 1.6 To understand cellular Organization of the Brain. 2.Teaching main and difficult points (1)The action and clinical use of phentolamine. (2)The adverse effects ofa-adrenergic blockers. (3)The pharmacologicalaction and clinical use of B-R blockers ISA.3.5 Features of selective β1 receptor blockers and β-adrenergic blockers with ISA. 4.Teaching Methods By using multimedia teaching method, off-line, on-line method, student-centered method and other diversified teaching methods, we inspire students to “learn with questions” and cultivate students’ critical thinking ability. 5.Teaching Evaluation Questions： 1. Why can phentolamine not be used in constitutional hypertension? 2. Can β-adrenergic blockers be used for heart failure clinically? 3. What are effects of rennin angiotensin system on the blood pressure? Chapter11 Introduction to the Pharmacology of CNS Drugs 1.Teaching Objectives 1.1 To learn methods for the Study of CNS Pharmacology. 1.2 To learn ion Channels & Neurotransmitter Receptors. 1.3 To learn central Neurotransmitters. 1.4 To learn sites of Drug Action. 1.5 To understand identification of Central Neurotransmitters. 1.6 To understand cellular Organization of the Brain. 2.Teaching main and difficult points (1) The action and clinical use of phentolamine. (2) The adverse effects of α-adrenergic blockers. (3) The pharmacological action and clinical use of β-R blockers ISA