BEH.462/3. 962J Molecular Principles of Biomaterials Spring 2003 o Applications biomaterials for bioengineering replication of trabecular bone structure and mechanical properties is still elusive low-cost, reproducible high-volume regenerative materials needed biomimetic structures are readily resorbed, promote vascularization and cellular biomaterials for other applications 8x8 Pieter Harting G original hand drawings of calcareous microstructures(1872) The complex morphology and microstructure of biological inorganic materials has long been appreciated o E.g. Harting s hand drawings from 1872 o natural organic/inorganic composites are used by nature as endo-and exo-sekeltons for their strong Lecture 11-Inorganic Biomaterials 2of12BEH.462/3.962J Molecular Principles of Biomaterials Spring 2003 Lecture 11 – Inorganic Biomaterials 2 of 12 o Applications: • biomaterials for bioengineering • replication of trabelcular bone structure and mechanical properties is still elusive • low-cost, reproducible high-volume regenerative materials needed • biomimetic structures are readily resorbed, promote vascularization and cellular differentiation • biomaterials for other applications Pieter HartingÕs original hand drawings of calcareous microstructures (1872) • The complex morphology and microstructure of biological inorganic materials has long been appreciated o E.g. Harting’s hand drawings from 1872 o natural organic/inorganic composites are used by nature as endo- and exo-sekeltons for their strong mechanical properties