(3)Dysfunction of renal endocrine (1 Increased secretion of rennin Renin↑ (2 Declined Kallikrein-kinin system(KKs) Kinin√ Increased secretion of endothelin ET↑ 4 Inadequate synthesis of prostaglandins from arachidonic acid PGE、I Renal Hypertension 1313 Renal Hypertension (3) Dysfunction of renal endocrine ① Increased secretion of rennin Renin  ③ Increased secretion of endothelin ET  ② Declined Kallikrein-kinin system (KKS) Kinin  ④ Inadequate synthesis of prostaglandins from arachidonic acid PGE2 , I2 