Control of Gene Expression: Promoters Every gene has a promoter the dna sequence immediately surrounding the transcription start site. The promoter is the site where RNa polymerase and the so-called general transcription factors bind coactivators general transcription factors RNA polymerase TAtA box coding region promoter RNA transcript Department of Biochemistry Molecular Biology eDepartment of Biochemistry & Molecular Biology 8 Control of Gene Expression: Promoters Every gene has a promoter, the DNA sequence immediately surrounding the transcription start site. The promoter is the site where RNA polymerase and the so-called general transcription factors bind