Genetic factors Familial clustering of endometriosis is a common clinical observation In families with endometriosis the disease is often confined to the maternal line, and is 7 times more common in first-degree relatives than in the general population In future studies, evaluation of dNa polymorphism may identify specific genes involved in the development of endometriosis 2003-11-3 62003-11-3 6 Genetic factors: • Familial clustering of endometriosis is a common clinical observation. • In families with endometriosis,the disease is often confined to the maternal line,and is 7 times more common in first-degree relatives than in the general population. • In future studies,evaluation of DNA polymorphism may identify specific genes involved in the development of endometriosis