Peculiar drug reaction in newborn 2.Hemolysis,jaundice caused by drugs Metabolism in liver rifampicin Globin 珠蛋白 novobiocin Free Porphyrin Bilirubin ive Hemoglobin 卟啉 胆红素 iron铁 conjunction type Erythrocyte of Bilirubin 结合型胆红素 Eliminate from Stability of erythrocyte membrane Intestinal tract ·Synthtic vitamin K Suppress Bowl movemrnt ·Sulfonamides磺胺类 Kill normal flora in intestinal 10 tractFree Porphyrin Globin 珠蛋白 Bilirubin Metabolism in liver • rifampicin • novobiocin 2. Hemolysis, jaundice caused by drugs Peculiar drug reaction in newborn liver 10 Free Hemoglobin iron铁 Porphyrin 卟啉 Bilirubin 胆红素 conjunction type of Bilirubin 结合型胆红素 Eliminate from Intestinal tract • Synthtic vitamin K Synthtic vitamin K • Sulfonamides 磺胺类 Sulfonamides 磺胺类 • Suppress Bowl movemrnt Suppress Bowl movemrnt • Kill normal flora in intestinal tract Stability of erythrocyte membrane liver Erythrocyte