Peculiar drug reaction in newborn 1.Hypersensitive reaction e.g. Morphine respiratory depression Underdeveloped central nervous system, e Digitalis and Salicylate are Toxic Underdeveloped renal excretion and high plasma concentration 91. Hypersensitive reaction Morphine respiratory depression Underdeveloped central nervous system, Peculiar drug reaction in newborn e.g. 9 Digitalis and Salicylate are Toxic Underdeveloped renal excretion and high plasma concentration