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(1)Sequential Reactions:ordered sequential mechanism 有序序列机制 Sequential Reactions:a ternary complex of the enzyme and both substrates forms.所有底物都可结合到酶上,然后 再形成产物 Ordered:the substrates bind the enzyme in a defined sequence. +NADH+Ht三HO—C—H+NAD* CH3 CH3 Pyruvate Lactate 乳酸脱氢酶,结合底物是有序的、释放产物也是有序的。The enzyme exists as a ternary complex:first,consisting of the enzyme and substrates and,after catalysis,the enzyme and products. NADH Pyruvate Lactate NAD+ Enzyme Enzyme E(NADH)(pyruvate) E(lactate)(NAD+)(1) Sequential Reactions: ordered sequential mechanism 有序序列机制) Sequential Reactions: a ternary complex of the enzyme and both substrates forms. 所有底物都可结合到酶上,然后 再形成产物 Ordered: the substrates bind the enzyme in a defined sequence. 乳酸脱氢酶,结合底物是有序的、释放产物也是有序的。The enzyme exists as a ternary complex: first, consisting of the enzyme and substrates and, after catalysis, the enzyme and products
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