Mechanism:Allostery变构 Enzyme Allosteric site Substrate-binding site When the effector Allosteric Substrate effector combines with the Conformational change in substrate-binding site; Enzyme reaction enzyme reaction allosteric site,the proceeds inhibited conformation of the enzyme is altered so Substrate cannot bind that the substrate can no longer bind. No enzyme reaction Enzyme reactionMechanism: Allostery 变构 When the effector combines with the allosteric site, the conformation of the enzyme is altered so that the substrate can no longer bind