5.2 Antimycotic antibiotics 521 Ampotericin B(AMB)(两性霉素B) OH OH OH O OHOH OHoH O HOOC H 0 O NH OH OH AMB was marked in 1951s, is most commonly antibiotics used to treatment systemic fungal infections and is the only polyene antibiotic antifungal agents for injection use5.2 Antimycotic antibiotics 5.2.1 Ampotericin B(AMB)(两性霉素B) O O O OH H HOOC OH OH OH OH OH OH OH O O CH3 OH NH2 OH AMB was marked in 1951’s, is most commonly antibiotics used to treatment systemic fungal infections and is the only Polyene antibiotic antifungal agents for injection use