9. Which of the following is a false statement a) Most SNPs have only two alleles b) Microsatellites and minisatellites usually have many alleles c)Microsatellites are often used as genetic markers in pedigree-based linkage studies d)SNPs are often used for genetic finger printing of forensic DNA samples e)SNPs are often used as genetic markers in genomewide association studies 10. Which of the following is not considered to be complex disorder? a) Cancer b) Huntingtons disease c)Alzheimer's disease d) Parkinsons disease e)Type-2 diabetes 11. Which of the following is a false statement? a)Somatic cells each contain roughly 200-2000 mitochondria b) Mitochondria carry out many important cellular functions, including the production of ATP, oxidation of fatty acids, regulation of intracellular Ca levels and regulation of c)Mitochondria are also the source of beneficial free radicals d) Sperm contain approximately 100 mitochondria and oocytes approximately 100,000 mitochondria e)All of our cells contain mitochondria inherited exclusively from our mother 12. Which of the following is a false statement? a)The mitochondrial genome comprises circular double-stranded DNA containing 166k b)The mitochondrial genome includes 37 genes: 13 protein coding genes, 22 tRNA genes and 2 ribosomal RNA genes c)Mitochondrial genes do not contain introns d) Mitochondria use the universal genetic code for the translation of proteins. e)Mitochondrial tRNAs contain special modifications to allow the recognition of"wobble Nucleotides within degenerate codons. 13. which of the following is a false statement? a)Mitochondrial DNA is replicated by DNA polymerase-gamma b)dNa polymerase-gamma is encoded in the nuclear genome c)Mutations in DNA polymerase-gamma are the cause of several mitochondrial disorders, including, chronic progressive external ophthalmoplegia(CPEO) d) CPeO symptoms include the inability to move the eyes and the inability to fully open the eyelids e)CPEO is always inherited from the mother9. Which of the following is a false statement? a) Most SNPs have only two alleles. b) Microsatellites and minisatellites usually have many alleles. c) Microsatellites are often used as genetic markers in pedigree-based linkage studies. d) SNPs are often used for genetic finger printing of forensic DNA samples. e) SNPs are often used as genetic markers in genomewide association studies. 10. Which of the following is not considered to be complex disorder? a) Cancer b) Huntington’s disease c) Alzheimer’s disease d) Parkinson’s disease e) Type-2 diabetes 11. Which of the following is a false statement? a) Somatic cells each contain roughly 200 -2000 mitochondria. b) Mitochondria carry out many important cellular functions, including the production of ATP, oxidation of fatty acids, regulation of intracellular Ca2+ levels and regulation of apoptosis. c) Mitochondria are also the source of beneficial free radicals. d) Sperm contain approximately 100 mitochondria and oocytes approximately 100,000 mitochondria. e) All of our cells contain mitochondria inherited exclusively from our mother. 12. Which of the following is a false statement? a) The mitochondrial genome comprises circular double-stranded DNA containing 16.6 k bp b) The mitochondrial genome includes 37 genes: 13 protein coding genes, 22 tRNA genes and 2 ribosomal RNA genes. c) Mitochondrial genes do not contain introns. d) Mitochondria use the universal genetic code for the translation of proteins. e) Mitochondrial tRNAs contain special modifications to allow the recognition of “wobble” Nucleotides within degenerate codons. 13. Which of the following is a false statement? a) Mitochondrial DNA is replicated by DNA polymerase-gamma. b) DNA polymerase-gamma is encoded in the nuclear genome. c) Mutations in DNA polymerase-gamma are the cause of several mitochondrial disorders, including, chronic progressive external ophthalmoplegia (CPEO). d) CPEO symptoms include the inability to move the eyes and the inability to fully open the eyelids. e) CPEO is always inherited from the mother