8.1.Mechanisms of heat inactivation of microorganisms Core Coar Activation Germination Outgrowth Sporulation endospores germinated endospore vegetative sporulated cell cell GeotoioanoftaeteoalcentosroiThe,"2ewem events as seen in electron microscopy and the lower row events as observed in phase contrast microscopy.Sporulation is not initiated until the end of a batch process.8.1. Mechanisms of heat inactivation of microorganisms