To master the chemical structures,drug design,structure-activity relationships,and mechanism of actions of major cholinergic drugs:Understand the synthesis and metabolism of major cholinergic drugs Including the following specific drugs: Muscarinic Agonists:Methacholine Chloride;Carbachol;Bethanechol Chloride;Pilocarpine;Cevimeline Acetylcholinesterase Inhibitors:Neostigmine;Rivastigmine;Tacrine;Galantamine;Donepezil; Muscarinic Antagonists:Atropine and its Analogues;Tiotropium bromide;Artane;Benztropine 2.2 Adrenergic Receptors and Drugs Affecting Adrenergic Neurotransmission Get a general idea about adrenaline and its functions and neurochemistry,and the distribution,structures and functions of norepinephrine receptor. Understand the development history of drugs affecting adrenergic neurotransmission. To master the chemical structures,drug design,structure-activity relationships,and mechanism of actions of major drugs affecting adrenergic neurotransmission;Understand the synthesis and metabolism of major drugs affecting adrenergic neurotransmission Including the following specific drugs: Alphal Adrenergic Agonists:Phenylethanolamines;2-Arylimidazolines Alpha2 Adrenergic Agonists:2-Aminoimidazolines (e.g.Clonidine) Betal Adrenergic Agonists:Dobutamine Beta2 Adrenergic Agonists:Phenylethanolamines (e.g.Isoproterenol;albuterol,salmeterol) Alphal Adrenergic Antagonists:Prazosin Beta Adrenergic Antagonists:aryloxypropanolamines (e.g.Propranolol;Metoprolol) 2.3 Serotonin receptors and Drugs Affecting Serotonergic Neurotransmission Get a general idea about serotonin and its functions and neurochemistry,and the distribution,structures and functions of serotonin receptor. Understand the development history of drugs affecting serotonergic neurotransmission. To master the chemical structures,drug design,structure-activity relationships,and mechanism of actions of major drugs affecting serotonergic neurotransmission;Understand the synthesis and metabolism of major drugs affecting serotonergic neurotransmission Including the following specific drugs: 5-HTIA Receptor Agonists:Buspirone,gepirone,ipsapirone;Vilazodone 5-HTID Agonists:SumatriptanTo master the chemical structures, drug design, structure-activity relationships, and mechanism of actions of major cholinergic drugs; Understand the synthesis and metabolism of major cholinergic drugs Including the following specific drugs: Muscarinic Agonists: Methacholine Chloride; Carbachol; Bethanechol Chloride; Pilocarpine; Cevimeline Acetylcholinesterase Inhibitors: Neostigmine; Rivastigmine; Tacrine; Galantamine; Donepezil; Muscarinic Antagonists: Atropine and its Analogues; Tiotropium bromide; Artane; Benztropine. 2.2 Adrenergic Receptors and Drugs Affecting Adrenergic Neurotransmission Get a general idea about adrenaline and its functions and neurochemistry, and the distribution, structures and functions of norepinephrine receptor. Understand the development history of drugs affecting adrenergic neurotransmission. To master the chemical structures, drug design, structure-activity relationships, and mechanism of actions of major drugs affecting adrenergic neurotransmission; Understand the synthesis and metabolism of major drugs affecting adrenergic neurotransmission Including the following specific drugs: Alpha1 Adrenergic Agonists: Phenylethanolamines; 2-Arylimidazolines Alpha2 Adrenergic Agonists: 2-Aminoimidazolines (e.g. Clonidine) Beta1 Adrenergic Agonists: Dobutamine Beta2 Adrenergic Agonists: Phenylethanolamines (e.g. Isoproterenol; albuterol, salmeterol) Alpha1 Adrenergic Antagonists: Prazosin Beta Adrenergic Antagonists: aryloxypropanolamines (e.g. Propranolol; Metoprolol) 2.3 Serotonin receptors and Drugs Affecting Serotonergic Neurotransmission Get a general idea about serotonin and its functions and neurochemistry, and the distribution, structures and functions of serotonin receptor. Understand the development history of drugs affecting serotonergic neurotransmission. To master the chemical structures, drug design, structure-activity relationships, and mechanism of actions of major drugs affecting serotonergic neurotransmission; Understand the synthesis and metabolism of major drugs affecting serotonergic neurotransmission Including the following specific drugs: 5-HT1A Receptor Agonists: Buspirone, gepirone, ipsapirone; Vilazodone 5-HT1D Agonists: Sumatriptan