COPD and Co-Morbidities Spilled Inflammation COPD patients are at increased risk for Myocardial infarction angina Osteoporosis Respiratory infection Depression Diabetes Lung cancer COPD has significant extrapulmonary(systemic) effects including Weight loss Nutritional abnormalities Skeletal muscle dysfunction MBBS project, Zhongshan HospitalMBBS project, Zhongshan Hospital COPD and Co-Morbidities —Spilled Inflammation COPD patients are at increased risk for: • Myocardial infarction, angina • Osteoporosis • Respiratory infection • Depression • Diabetes • Lung cancer COPD has significant extrapulmonary (systemic) effects including: • Weight loss • Nutritional abnormalities • Skeletal muscle dysfunction