2.酰基化反应属亲核取代反应(参见P249氨解反应) 伯胺 CH3CH2NH2+CH3COCl→→CH3 CONHCH2CH3+HCl N乙基乙酰胺(与胺成盐) NH2+(CH3CO)2O—→ NHCOCH3 乙酰苯胺 +CH3COOH(与胺成盐) 仲胺 (CH3CH2)2NH +(CH3CO)2O (CH3CH2)2NCOCH +CH3COOH(与胺成盐) 叔胺:不发生酰基化反应(∵叔胺N上无H 3.磺酰化反应(了解)2. 酰基化反应 属亲核取代反应(参见P249 氨解反应) 伯胺: CH3CH2NH2 + CH3COCl CH3CONHCH2CH3 + HCl N–乙基乙酰胺 (与胺成盐) –NH2 + (CH3CO)2O –NHCOCH3 乙酰苯胺 + CH3COOH (与胺成盐) 仲胺: (CH3CH2 )2NH + (CH3CO)2O (CH3CH2 )2NCOCH3 + CH3COOH (与胺成盐) 叔胺: 不发生酰基化反应 (∵ 叔胺 N上无H) 3. 磺酰化反应 (了解)