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Fish Shelf immuol, 1998, 8: 409- and the response of rainbow trout, Oncorhynchus mykiss to infec [36 Durve V LOvell R T, Vitamin C and disease resistance in char tion with Yersinia hacken J].J Fish Bio, 1992, 41: 10371041 [47] Ortum J, Esteban M A Meseguer J. High dietary intake of d-tooo ,39:948-951 pherol acetate enhances the mrr specific immune response of gilt- [37] Lim C, Kesius P H Li M H, et al. Interaction between dietary head seabream( Spana arata L)[J]. Fish Shelf Immunol vels of iron and vitamin C on growth, hematology immune re- sponse and resistance of channel catfish( Ictaluri punctatus)to [48 Cuesta A, Esteban M A Orum J, et al. Vitamin E and disease Edwardsiella ictaluri challenge J]. Aquac, 2000, 185: 313-327. resistance in channel catfish( Iaaimuas punctatus)[J]Can J Fish [38] Erdal J I, Evensen O, KaurstadO K, et al. Relationship between Aquat Sci2001,39:948951 diet and sponse in Atlantic salmon( Salmo salar L. [49] Thompson KD, Tatner M F. Hifects of dietary r 3 polyunsaturated after feeding vanous levels of ascorbic acid and omer 3 fatty acids atty acid ratio on immune response of Altantic salon, Saimo sal- ]- Aquac,1991,98:363379 [] Aquac Nur,1996,2(1):21-31 139] Andersen F, ygren B, Maage A, et a. Interaction between two [50] Sheldon WM, Blazer VS. Intluence of dietary lipid and tempera two forms of ascorbic acid and the effect ure on bactericidal activity of channel catfish macrophage J]-J on growth, antioxidant status and some mn specific immune par- quat Anim Health, 199113: 87-93 rameters in Atlantic salmon Salmo salar) salts[J]. Aquac [51] Mntero D, Kalimmwski T, Obach A, et al. Vegetable lipid sources 8,161:43745 for gilthead seabream Spate arata): effects on fish health PJ) [40 Wise DJ, Tomasso JR. Efects of dietary selenium and vitamin E Aquac,2003,225:353370 on red blood cell peroxidation, glutathione perocidase activity and [52] Thompson K D, Tatner M F, Henderson RJ. Efects of dietary macrophage superoxde anion production in channel catfish [J].J (rr 3)and (r6) polyunsaturated fatty acid ratio on the immune Aquat Aniam Health, 1993, 5: 177182 sponse of Atlantic salon, Salmo salar L [J]. Aquac Nutr [41] Wise D J, Tomasso R, Schedler T E Elect of vitamin Eon 996,2:21-31 he immune response of Turbot to Edwardsiella ictal [J].J 53]Kiron v, fukuda H, Takeuchi, et al. Essential fatty acid nutrition Aquat Anim Health 1993, 5: 183-188. and defence mechanisms in rainbow trout. OncordnnchIss kiss [42] Obach A, Quentel F C. Elect of a-tooopheol and dietary oxidized J]- Comp Biochem Physiol, 1995, 111: 361-367. fish oil on the immune response of sea bass Dicentrarchs labrax [54] Li M H, Wise DJ Johnson M R, et al. Dietary menhaden oil re- U]. Dis Aquat Orgnism, 1993, 15: 175-18 duced resistance of channel catfish( Ictalurus punctatus)to Eat [43 Blazer V S. Piscine macrophage function and nutritional influenc- wardsiella ictaluri J]. Aquac, 1994, 128: 33 o1994-2007chinaAcademicJOurnalElectronicPublishingHouse.Allrightsreservedhttp://www.cnki.net[33 ] Roberts M L ,Davies S J ,Pulsford A L1 The influence of ascorbic acid on non2 specific immunity in the turbot ( Scophthalmus maci2 mus L. ) [J ]1Fish Shellf Immunol ,1995 ,5 :272381 [34 ] Li M H ,Wise D J ,Robinson E H1 Effect of dietary vitamin C on weight gain tissue ascorbate concentration ,stress response and dis2 ease resistance of channel catfish Ictaiurus punctatus [J ]1J World Aquac Soc , 1998 ,29(1) :1281 [ 35 ] Verlhac V ,Obach A ,Gabaudan J , et al1 Immunomodulation by di2 etary vitamin C and glucan in rainbow trout ( Oncorhynchus mykiss) [J ]1Fish Shellf immunol , 1998 ,8 :40924241 [36 ] Durve V S ,Lovell R T , Vitamin C and disease resistance in chan2 nel catfish ( Ictalurus punctatus) [ J ] 1Can J Fish Aquat Sci , 1982 ,39 :94829511 [37 ] Lim C , Klesius P H ,Li M H , et al1 Interaction between dietary levels of iron and vitamin C on growth ,hematology ,immune re2 sponse and resistance of channel catfish ( Ictalurus punctatus) to Edwardsiella ictaluri challenge [J ]1Aquac , 2000 ,185 :31323271 [38 ] Erdal J I , Evensen O , Kaurstad O K, et al1Relationship between diet and immune response in Atlantic salmon ( Salmo salar L. ) after feeding various levels of ascorbic acid and omega23 fatty acids [J ]1Aquac ,1991 ,98 :36323791 [39 ] Andersen F ,Lygren B ,Maage A , et al1 Interaction between two dietary levels of iron and two forms of ascorbic acid and the effect on growth ,anti2oxidant status and some non specific immune pa2 rameters in Atlantic salmon ( Salmo salar) smolts [J ] 1Aquac , 1998 ,161 :43724511 [40 ] Wise D J ,Tomasso J R1 Effects of dietary selenium and vitamin E on red blood cell peroxidation ,glutathione perocidase activity ,and macrophage superoxide anion production in channel catfish [J ]1J Aquat Aniam Health ,1993 , 5 :17721821 [41 ] Wise D J , Tomasso J R , Schwedler T E1 Effect of vitamin E on the immune response of Turbot to Edwardsiella ictaluri [J ] . J Aquat Anim Health , 1993 , 5 :18321881 [42 ] Obach A ,Quentel F C1Effect ofα2tocopherol and dietary oxidized fish oil on the immune response of sea bass Dicentrarchus Iabrax [J ]1Dis Aquat Orgnism , 1993 ,15 :17521851 [43 ] Blazer V S1 Piscine macrophage function and nutritional influenc2 es :a review [J ]1J Aquat Anim Health , 1991 ,3 :772861 [44 ] Ortuno J ,Cueaa A ,Esteban M A , et al1 Effect of oral administra2 tion of high vitamin C and E dosages on the gilthead seabream ( Sparus aurata L1) innate immune system [J ]1Vet Immunol Im2 munopathol , 2001 ,79 :16721801 [45 ] Hardie L J ,Fletcher T C ,Secombes C J1 The effect of vitamin E on the immune response of Atlantic salmon ( Salmo salar) [J ]1 Aquac , 1990 ,87 :12131 [46 ] Furones M D ,Alderman D J ,Bucke D , et al1 Dietary vitamin E and the response of rainbow trout , Oncorhynchus mykiss to infec2 tion with Yersinia ruckeri [J ] .J Fish Bio ,1992 , 41 :1037210411 [47 ] Ortuno J ,Esteban M A ,Meseguer J1High dietary intake ofα2toco2 pherol acetate enhances the non2specific immune response of gilt2 head seabream ( Sparus aurata L. ) [J ] 1Fish Shellf Immunol , 2000 ,10 :29323071 [48 ] Cuesta A , Esteban M A ,Ortuno J , et al1Vitamin E and disease resistance in channel catfish ( Ictalurus punctatus) [J ]1Can J Fish Aquat Sci ,2001 ,39 :94829511 [49 ] Thompson K D , Tatner M F1Effects of dietary n23 polyunsaturated fatty acid ratio on immune response of Altantic salmon , Salmo sal2 ar L. [J ]1 Aquac Nutr ,1996 ,2(1) :212311 [50 ] Sheldon W M ,Blazer V S1 Influence of dietary lipid and tempera2 ture on bactericidal activity of channel catfish macrophage [J ] 1J Aquat Anim Health , 1991 ,3 :872931 [51 ] Montero D ,Kalimowski T ,Obach A , et al1 Vegetable lipid sources for gilthead seabream ( Spatus aurata) :effects on fish health [J ]1 Aquac ,2003 , 225 :35323701 [52 ] Thompson K D , Tatner M F , Henderson R J1 Effects of dietary (n23) and (n26) polyunsaturated fatty acid ratio on the immune response of Atlantic salmon , Salmo salar L. [J ] 1 Aquac Nutr , 1996 , 2 : 212311 [53 ] Kiron v ,fukuda H ,Takeuchi , et al1 Essential fatty acid nutrition and defence mechanisms in rainbow trout , Oncorhynchus mkiss [J ]1Comp Biochem Physiol , 1995 ,111 :36123671 [54 ] Li M H ,Wise D J ,Johnson M R , et al1 Dietary menhaden oil re2 duced resistance of channel catfish ( Ictalurus punctatus) to Ed2 wardsiella ictaluri [J ]1Aquac ,1994 , 128 :33523441 第 27 卷 第 3 期 王桂芹等 :鱼类免疫增强剂的研究现状 943