Main Forces behind metagenomics O High-throughput sequencing technologies sequencing 1 million nucleotide bases of dna decreased from $10,000 to $o 10 uS dollars between 2001 and 2011 Sequence data of microbe reference strains o Advanced bioinformatical analytic tools and pipelines o High-throughput screening technologiesMain Forces behind Metagenomics  High-throughput sequencing technologies  sequencing 1 million nucleotide bases of DNA decreased from $10,000 to $0.10 US dollars between 2001 and 2011  Sequence data of microbe reference strains  Advanced bioinformatical analytic tools and pipelines  High-throughput screening technologies