1H-NMR 端 Facts about chemical shifts and coupling constants 。 Preparation of NMR Samples NMR is of analysis is shorter instruments are always ready fo NMR instruments are quite versatile:with measurement,without any preceding the proper design,they can accommodate conditioning or calibration procedure solid,liquid or gas phase samples;even living being necessary. organisms can be measured.You will be making liquid samples. 8 243 244 245 2 O 3 1 4 5 8 O 7 6 1' 6' 2' 5' 3' 4' O O 7' O O H H 246 Facts about chemical shifts and coupling constants: Chemical shifts in d ppm are independent of the strength of the applied field Bo and correspondingly, the instrument operating frequency. Chemical shifts in Hz are field and frequency dependent. Coupling constants J in Hz are field and frequency independent. Coupling constants J in d ppm are field and frequency dependent. 247 NMR is more robust and the time of analysis is shorter because the NMR instruments are always ready for measurement, without any preceding conditioning or calibration procedure being necessary. 248 Preparation of NMR Samples NMR instruments are quite versatile; with the proper design, they can accommodate solid, liquid or gas phase samples; even living organisms can be measured. You will be making liquid samples