Mechanism of Action of ACEI ●Afterload reduction ●Preload reduction Reduction of facilitation of sympathetic nervous system o Reduction of cardiac hypertrophy Drugs of choice in heart failure (with diuretics) Current investigational use:Acute myocardial infarctionMechanism of Action Mechanism of Action of ACEI of ACEI  Afterload reduction  Preload reduction  Reduction of facilitation of sympathetic nervous system  Reduction of cardiac hypertrophy  Drugs of choice in heart failure (with diuretics)  Current investigational use: Acute myocardial infarction