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Preparation of Alkenes:Elimination Reaction A.Dehydration of alcohols 1.Zaitsev rule:regioselectivity and stereoselectivity -the major product from B-elimination is the more stable alkene 人 s0人 regioselective O 90% 10% OH HaPO4 major minor H2S04, △ OH 56% 32% 12% stereoselective College of Science A. Dehydration of alcohols Preparation of Alkenes: Elimination Reactions 1. Zaitsev rule: regioselectivity and stereoselectivity -the major product from β-elimination is the more stable alken e OH + H 2SO 4 ∆ 90% 10% OH H 3PO 4 ∆ + OH + + H 2SO 4 ∆ 56% 32% 12% major minor regioselective stereoselective
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