HIV types and subtypes HIV's genome is highly variable Reverse transcriptase of Hiv does not have proofreading activity HIV has two types: HIV-1 and HIv-2 HIV-1 is more common more virulent and more infectious than hiv-2 Each type has many subtypes R Global Total 32%53% 53% 26.7% 472%(2.3% 口 Subtype A口 Subtype B口 Subtype C 口 Subtype D口 CRF AE■ Others www.wikidoc.orgHIV types and subtypes www.wikidoc.org • HIV’s genome is highly variable • Reverse transcriptase of HIV does not have proofreading activity • HIV has two types: HIV-1 and HIV-2 • HIV-1 is more common, more virulent and more infectious than HIV-2 • Each type has many subtypes