DETAILED CONTENTS 99 Nucleophilic Aromatic Substitution 303 9-10 Oxidation and Reduction of Aromatic Compounds 306 911 An Introduction to Organic Synthesis:Polysubstituted Benzenes 308 SOMETHING EXTRA Aspirin,NSAIDs,and COX-2 Inhibitors 314 Structure Determination: Mass Spectrometry,Infrared Spectroscopy, and Ultraviolet Spectroscopy 319 10-1 Mass Spectrometry of Small Molecules:Magnetic-Sector Instruments 320 10-2 Interpreting Mass Spectra 10-3 Mass Spectrometry of Some Common Functional Groups 10-4 Mass Spectrometry in Biological Chemistry:Time-of-Flight(TOF) Instruments 328 10-5 Spectroscopy and the Electromagnetic Spectrum 329 10-6 Infrared Spectroscopy 332 10-7 Interpreting Infrared Spectra 3 10-8 Infrared Spectra of Some Common Functional Groups 37 10-9 Ultraviolet Spectroscopy 34 10-10 Interpreting Ultraviolet Spectra:The Effect of Conjugation 10-11 Conjugation,Color,and the Chemistry ofVision 346 SOMETHING EXTRA X-Ray Crystallography Structure Determination:Nuclear Magnetic Resonance Spectroscopy 350 1l-1 Nuclear Magnetic Resonance Spectroscopy 350 11-2 The Nature of NMR Absorptions 11-3 Chemical Shifts 55 11-4 13C NMR Spectroscopy:Signal Averaging and FT-NMR 3 1-5 Characteristics of13C NMR Spectroscopy 358 11-6 DEPT 13C NMR Spectroscopy 11-7 Uses of 13C NMR Spectroscopy 364 1-8 H NMR Spectroscopy and Proton Equivalence 365 119 Chemical Shifts in IH NMR Spectroscopy 368 x DetaileD Contents 9-9 nucleophilic aromatic substitution 303 9-10 oxidation and Reduction of aromatic compounds 306 9-11 an introduction to organic synthesis: polysubstituted Benzenes 308 soMetHinG eXtra aspirin, nsaiDs, and coX-2 inhibitors 314 10 structure Determination: Mass spectrometry, infrared spectroscopy, and Ultraviolet spectroscopy | 319 10-1 Mass spectrometry of small Molecules: Magnetic-sector instruments 320 10-2 interpreting Mass spectra 321 10-3 Mass spectrometry of some common Functional groups 326 10-4 Mass spectrometry in Biological chemistry: time-of-Flight (toF) instruments 328 10-5 spectroscopy and the Electromagnetic spectrum 329 10-6 infrared spectroscopy 332 10-7 interpreting infrared spectra 334 10-8 infrared spectra of some common Functional groups 337 10-9 Ultraviolet spectroscopy 342 10-10 interpreting Ultraviolet spectra: the Effect of conjugation 345 10-11 conjugation, color, and the chemistry of Vision 346 soMetHinG eXtra X-Ray crystallography 348 11 structure Determination: nuclear Magnetic resonance spectroscopy | 350 11-1 nuclear Magnetic Resonance spectroscopy 350 11-2 the nature of nMR absorptions 352 11-3 chemical shifts 355 11-4 13c nMR spectroscopy: signal averaging and Ft-nMR 357 11-5 characteristics of 13c nMR spectroscopy 358 11-6 DEpt 13c nMR spectroscopy 361 11-7 Uses of 13c nMR spectroscopy 364 11-8 1 h nMR spectroscopy and proton Equivalence 365 11-9 chemical shifts in 1 h nMR spectroscopy 368 42912_00_FM_i-xxiv.indd 10 1/16/14 3:00 PM Copyright 2015 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. Due to electronic rights, some third party content may be suppressed from the eBook and/or eChapter(s). Editorial review has deemed that any suppressed content does not materially affect the overall learning experience. Cengage Learning reserves the right to remove additional content at any time if subsequent rights restrictions require it