7.91 April 1, 2004 Amy Keating Introduction to protein Structure Classification Protein structures basics Where to find them how to look at them what they can tell you structural and evolutionary Comparisons PDB ID: 1HCL SchuIze-Gahmen, U, J Brandsen, H. D. Jones, D. O Morgan, L Meijer, J. Vesely, S.H. Kim. "Multiple Modes of Ligand Recognition: Crystal Structures of Cyclin-dependent Protein Kinase 2 in Complex with ATP and Two Inhibitors, Olomoucine and Isopentenyladenine. "Proteins 22 (1995): 378 TheProteinDataBank(pdb-http://www.pdb.org/)isthesingleworldwiderepositoryfortheprocessinganddistributionof3-dbiologicalmacromolecularstructuredata Berman, H. M.,J. Westbrook, Z Feng, G Gilland, T N. Bhat, H Weissig, I N. Shindyalov, and P. E Bourne. The Protein Data Bank. Nucleic Acids Research 28 (2000):235-242 (pDbAdvisoryNoticeonusingmaterialsavailableinthearchivehttp://www.rcsb.org/pdb/advisory.html7.91 April 1, 2004 Amy Keating Introduction to Protein Structure & Classification Protein structures basics where to find them how to look at them what they can tell you structural and evolutionary comparisons PDB ID: 1HCL Schulze-Gahmen, U., J. Brandsen, H. D. Jones, D. O. Morgan, L. Meijer, J. Vesely, S. H. Kim. "Multiple Modes of Ligand Recognition: Crystal Structures of Cyclin-dependent Protein Kinase 2 in Complex with ATP and Two Inhibitors, Olomoucine and Isopentenyladenine." Proteins 22 (1995): 378. The Protein Data Bank (PDB - http://www.pdb.org/) is the single worldwide repository for the processing and distribution of 3-D biological macromolecular structure data. Berman, H. M., J. Westbrook, Z. Feng, G. Gilliland, T. N. Bhat, H. Weissig, I. N. Shindyalov, and P. E. Bourne. The Protein Data Bank. Nucleic Acids Research 28 (2000): 235-242 . (PDB Advisory Notice on using materials available in the archive: http://www.rcsb.org/pdb/advisory.html)