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Inflamm Bowel Dis, 2015, 21: 2311-2319１２ ＣｈａｎＳＳ，ＬｕｂｅｎＲ，ＯｌｓｅｎＡ，ｅｔａｌ．Ａｓｓｏｃｉａｔｉｏｎｂｅｔｗｅｅｎｈｉｇｈ ｄｉｅｔａｒｙ ｉｎｔａｋｅ ｏｆ ｔｈｅ ｎ３ ｐｏｌｙｕｎｓａｔｕｒａｔｅｄ ｆａｔｔｙ ａｃｉｄ ｄｏｃｏｓａｈｅｘａｅｎｏｉｃａｃｉｄａｎｄｒｅｄｕｃｅｄｒｉｓｋｏｆＣｒｏｈｎ′ｓｄｉｓｅａｓｅ［Ｊ］． ＡｌｉｍｅｎｔＰｈａｒｍａｃｏｌＴｈｅｒ，２０１４，３９：８３４８４２． １３ ＬｅｖＴｚｉｏｎＲ，ＧｒｉｆｆｉｔｈｓＡＭ，ＬｅｄｅｒＯ，ｅｔａｌ．Ｏｍｅｇａ３ｆａｔｔｙａｃｉｄｓ （ｆｉｓｈｏｉｌ）ｆｏｒｍａｉｎｔｅｎａｎｃｅｏｆｒｅｍｉｓｓｉｏｎｉｎＣｒｏｈｎ′ｓｄｉｓｅａｓｅ［Ｊ］． ＣｏｃｈｒａｎｅＤａｔａｂａｓｅＳｙｓｔＲｅｖ，２０１４Ｆｅｂ２８；（２）：ＣＤ００６３２０． １４ ＴｙａｇｉＡ，ＫｕｍａｒＵ，ＲｅｄｄｙＳ，ｅｔａｌ．Ａｔｔｅｎｕａｔｉｏｎｏｆｃｏｌｏｎｉｃ ｉｎｆｌａｍｍａｔｉｏｎｂｙｐａｒｔｉａｌｒｅｐｌａｃｅｍｅｎｔｏｆｄｉｅｔａｒｙｌｉｎｏｌｅｉｃａｃｉｄｗｉｔｈ αｌｉｎｏｌｅｎｉｃａｃｉｄｉｎａｒａｔｍｏｄｅｌｏｆｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅ［Ｊ］． ＢｒＪＮｕｔｒ，２０１２，１０８：１６１２１６２２． １５ ＴｕｒｎｅｒＤ，Ｓｈａｈ ＰＳ，Ｓｔｅｉｎｈａｒｔ ＡＨ，ｅｔａｌ．Ｍａｉｎｔｅｎａｎｃｅｏｆ ｒｅｍｉｓｓｉｏｎｉｎｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅｕｓｉｎｇｏｍｅｇａ３ｆａｔｔｙ ａｃｉｄｓ （ｆｉｓｈｏｉｌ）：ａｓｙｓｔｅｍａｔｉｃｒｅｖｉｅｗａｎｄｍｅｔａａｎａｌｙｓｅｓ［Ｊ］． ＩｎｆｌａｍｍＢｏｗｅｌＤｉｓ，２０１１，１７：３３６３４５． １６ ＪａｎｔｃｈｏｕＰ，ＭｏｒｏｉｓＳ，ＣｌａｖｅｌＣｈａｐｅｌｏｎＦ，ｅｔａｌ．Ａｎｉｍａｌｐｒｏｔｅｉｎ ｉｎｔａｋｅａｎｄ ｒｉｓｋ ｏｆｉｎｆｌａｍｍａｔｏｒｙ ｂｏｗｅｌｄｉｓｅａｓｅ：Ｔｈｅ Ｅ３Ｎ ｐｒｏｓｐｅｃｔｉｖｅｓｔｕｄｙ ［Ｊ］． Ａｍ Ｊ Ｇａｓｔｒｏｅｎｔｅｒｏｌ，２０１０，１０５： ２１９５２２０１． １７ Ｇｌａｓｓｍａｎ ＭＳ，Ｎｅｗｍａｎ ＬＪ，ＢｅｒｅｚｉｎＳ，ｅｔａｌ．Ｃｏｗ′ｓ ｍｉｌｋ ｐｒｏｔｅｉｎｓｅｎｓｉｔｉｖｉｔｙｄｕｒｉｎｇｉｎｆａｎｃｙｉｎｐａｔｉｅｎｔｓｗｉｔｈｉｎｆｌａｍｍａｔｏｒｙ ｂｏｗｅｌｄｉｓｅａｓｅ［Ｊ］．ＡｍＪＧａｓｔｒｏｅｎｔｅｒｏｌ，１９９０，８５：８３８８４０． １８ ＳａｗｃｚｅｎｋｏＡ，ＳａｎｄｈｕＢＫ，ＬｏｇａｎＲＦ，ｅｔａｌ．Ｐｒｏｓｐｅｃｔｉｖｅｓｕｒｖｅｙ ｏｆｃｈｉｌｄｈｏｏｄｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅｉｎｔｈｅＢｒｉｔｉｓｈＩｓｌｅｓ［Ｊ］． Ｌａｎｃｅｔ，２００１，３５７：１０９３１０９４． １９ 史肖华，郑家驹，郭志荣，等．克罗恩病发病相关因素的病例对 照研究［Ｊ］．胃肠病学，２００８，１３：２９３２９６． ２０ ＷｉｅｃｅｋＳ，ＷｏｓＨ，ＲａｄｚｉｅｗｉｃｚＷＩ，ｅｔａｌ．Ｄｉｓａｃｃｈａｒｉｄａｓｅａｃｔｉｖｉｔｙ ｉｎｃｈｉｌｄｒｅｎ ｗｉｔｈｉｎｆｌａｍｍａｔｏｒｙ ｂｏｗｅｌｄｉｓｅａｓｅ［Ｊ］．Ｔｕｒｋ Ｊ Ｇａｓｔｒｏｅｎｔｅｒｏｌ，２０１４，２５：１８５１９１． ２１ ＶｅｒｎｉａＰ，ＬｏｉｚｏｓＰ，ＤｉＧｉｕｓｅｐｐａｎｔｏｎｉｏＩ，ｅｔａｌ．Ｄｉｅｔａｒｙｃａｌｃｉｕｍ ｉｎｔａｋｅｉｎｐａｔｉｅｎｔｓｗｉｔｈｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅ［Ｊ］．ＪＣｒｏｈｎｓ Ｃｏｌｉｔｉｓ，２０１４，８：３１２３１７． ２２ ＳｉｎｇｈＳＢ，ＬｉｎＨＣ．Ｈｙｄｒｏｇｅｎｓｕｌｆｉｄｅｉｎｐｈｙｓｉｏｌｏｇｙａｎｄｄｉｓｅａｓｅｓ ｏｆｔｈｅｄｉｇｅｓｔｉｖｅｔｒａｃｔ［Ｊ］．Ｍｉｃｒｏｏｒｇａｎｉｓｍｓ，２０１５，３：８６６８８９． ２３ ＦｅｃｔｅａｕＭＥ，ＰｉｔｔａＤＷ，ＶｅｃｃｈｉａｒｅｌｌｉＢ，ｅｔａｌ．Ｄｙｓｂｉｏｓｉｓｏｆｔｈｅ ｆｅｃａｌｍｉｃｒｏｂｉｏｔａｉｎｃａｔｔｌｅｉｎｆｅｃｔｅｄ ｗｉｔｈ ｍｙｃｏｂａｃｔｅｒｉｕｍ ａｖｉｕｍ ｓｕｂｓｐ．ｐａｒａｔｕｂｅｒｃｕｌｏｓｉｓ［Ｊ］．ＰＬｏＳＯｎｅ，２０１６，１１：ｅ１６０３５３． ２４ ＯｗｃｚａｒｅｋＤ，ＲｏｄａｃｋｉＴ，ＤｏｍａｇａａＲｏｄａｃｋａＲ，ｅｔａｌ．Ｄｉｅｔａｎｄ ｎｕｔｒｉｔｉｏｎａｌｆａｃｔｏｒｓｉｎｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅｓ［Ｊ］．ＷｏｒｌｄＪ Ｇａｓｔｒｏｅｎｔｅｒｏｌ，２０１６，２２：８９５９０５． ２５ ＳａｒｂａｇｉｌｉＳｈａｂａｔＣ，ＳｉｇａｌｌＢｏｎｅｈ Ｒ，Ｌｅｖｉｎｅ Ａ．Ｎｕｔｒｉｔｉｏｎａｌ ｔｈｅｒａｐｙ ｉｎ ｉｎｆｌａｍｍａｔｏｒｙ ｂｏｗｅｌ ｄｉｓｅａｓｅ ［Ｊ］． Ｃｕｒｒ Ｏｐｉｎ Ｇａｓｔｒｏｅｎｔｅｒｏｌ，２０１５，３１：３０３３０８． ２６ ＨａｎｓｅｎＴＳ，ＪｅｓｓＴ，ＶｉｎｄＩ，ｅｔａｌ．Ｅｎｖｉｒｏｎｍｅｎｔａｌｆａｃｔｏｒｓｉｎ ｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅ：ａｃａｓｅｃｏｎｔｒｏｌｓｔｕｄｙｂａｓｅｄｏｎａ Ｄａｎｉｓｈｉｎｃｅｐｔｉｏｎ ｃｏｈｏｒｔ［Ｊ］．Ｊ Ｃｒｏｈｎｓ Ｃｏｌｉｔｉｓ，２０１１，５： ５７７５８４． ２７ ＡｎａｎｔｈａｋｒｉｓｈｎａｎＡＮ，ＫｈａｌｉｌｉＨ，ＳｏｎｇＭ，ｅｔａｌ．Ｈｉｇｈｓｃｈｏｏｌ ｄｉｅｔａｎｄｒｉｓｋｏｆＣｒｏｈｎ′ｓｄｉｓｅａｓｅａｎｄｕｌｃｅｒａｔｉｖｅｃｏｌｉｔｉｓ［Ｊ］． ＩｎｆｌａｍｍＢｏｗｅｌＤｉｓ，２０１５，２１：２３１１２３１９． ２８ Ｓｃｈｒｅｎｋ Ｄ． Ｄｉｅｔａｒｙ ｆｉｂｅｒ， ｌｏｗｍｏｌｅｃｕｌａｒｗｅｉｇｈｔ ｆｏｏｄ ｃｏｎｓｔｉｔｕｅｎｔｓａｎｄｃｏｌｏｒｅｃｔａｌｉｎｆｌａｍｍａｔｉｏｎｉｎａｎｉｍａｌｍｏｄｅｌｓａ ｒｅｖｉｅｗ［Ｊ］．ＭｏｌＮｕｔｒＦｏｏｄＲｅｓ，２００９，５３：１２８１１２８８． ２９ ＬｉｕＸ，ＷｕＹ，ＬｉＦ，ｅｔａｌ．Ｄｉｅｔａｒｙｆｉｂｅｒｉｎｔａｋｅｒｅｄｕｃｅｓｒｉｓｋｏｆ ｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅ：ｒｅｓｕｌｔｆｒｏｍａ ｍｅｔａａｎａｌｙｓｉｓ［Ｊ］． ＮｕｔｒＲｅｓ，２０１５，３５：７５３７５８． ３０ ＲａｃｉｎｅＡ，ＣａｒｂｏｎｎｅｌＦ，ＣｈａｎＳＳ，ｅｔａｌ．Ｄｉｅｔａｒｙｐａｔｔｅｒｎｓａｎｄ ｒｉｓｋｏｆｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅｉｎＥｕｒｏｐｅ：ｒｅｓｕｌｔｓｆｒｏｍｔｈｅ ＥＰＩＣｓｔｕｄｙ［Ｊ］．ＩｎｆｌａｍｍＢｏｗｅｌＤｉｓ，２０１６，２２：３４５３５４． ３１ ＤｉｘｏｎＬＪ，ＫａｂｉＡ，ＮｉｃｋｅｒｓｏｎＫＰ，ｅｔａｌ．Ｃｏｍｂｉｎａｔｏｒｉａｌｅｆｆｅｃｔｓ ｏｆｄｉｅｔａｎｄｇｅｎｅｔｉｃｓｏｎｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅｐａｔｈｏｇｅｎｅｓｉｓ ［Ｊ］．ＩｎｆｌａｍｍＢｏｗｅｌＤｉｓ，２０１５，２１：９１２９２２． ３２ ＰｅｄｅｒｓｅｎＮ，ＡｎｋｅｒｓｅｎＤ，ＦｅｌｄｉｎｇＭ，ｅｔａｌ．ＬｏｗＦＯＤＭＡＰｄｉｅｔ ｒｅｄｕｃｅｓｉｒｒｉｔａｂｌｅｂｏｗｅｌｓｙｍｐｔｏｍｓａｎｄｉｍｐｒｏｖｅｓｑｕａｌｉｔｙｏｆｌｉｆｅｉｎ ｐａｔｉｅｎｔｓ ｗｉｔｈｉｎｆｌａｍｍａｔｏｒｙ ｂｏｗｅｌｄｉｓｅａｓｅｉｎ ａ ｒａｎｄｏｍｉｚｅｄ ｃｏｎｔｒｏｌｌｅｄ ｔｒｉａｌ：５５ｔｈ Ａｎｎｕａｌ Ｍｅｅｔｉｎｇ ｏｆｔｈｅ Ｓｏｃｉｅｔｙｆｏｒ ＳｕｒｇｅｒｙｏｆｔｈｅＡｌｉｍｅｎｔａｒｙＴｒａｃｔ （ＳＳＡＴ）／Ｄｉｇｅｓｔｉｖｅ Ｄｉｓｅａｓｅ Ｗｅｅｋ（ＤＤＷ），Ｃｈｉｃａｇｏ，ＩＬ，２０１４［Ｃ］． ３３ ＣｈａｎＳＳ，ＬｕｂｅｎＲ，ｖａｎＳｃｈａｉｋＦ，ｅｔａｌ．Ｃａｒｂｏｈｙｄｒａｔｅｉｎｔａｋｅｉｎ ｔｈｅｅｔｉｏｌｏｇｙｏｆＣｒｏｈｎ′ｓｄｉｓｅａｓｅａｎｄｕｌｃｅｒａｔｉｖｅｃｏｌｉｔｉｓ［Ｊ］．Ｉｎｆｌａｍｍ ＢｏｗｅｌＤｉｓ，２０１４，２０：２０１３２０２１． ３４ Ａｎａｎｔｈａｋｒｉｓｈｎａｎ ＡＮ，Ｋｈａｌｉｌｉ Ｈ，Ｋｏｎｉｊｅｔｉ ＧＧ，ｅｔ ａｌ． Ａ ｐｒｏｓｐｅｃｔｉｖｅｓｔｕｄｙｏｆｌｏｎｇｔｅｒｍｉｎｔａｋｅｏｆｄｉｅｔａｒｙｆｉｂｅｒａｎｄｒｉｓｋｏｆ Ｃｒｏｈｎ′ｓｄｉｓｅａｓｅａｎｄｕｌｃｅｒａｔｉｖｅｃｏｌｉｔｉｓ［Ｊ］．Ｇａｓｔｒｏｅｎｔｅｒｏｌｏｇｙ， ２０１３，１４５：９７０９７７． ３５ ＷｅｄｌａｋｅＬ，Ｓｌａｃｋ Ｎ，Ａｎｄｒｅｙｅｖ ＨＪ，ｅｔａｌ．Ｆｉｂｅｒｉｎ ｔｈｅ ｔｒｅａｔｍｅｎｔａｎｄ ｍａｉｎｔｅｎａｎｃｅｏｆｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅ：ａ ｓｙｓｔｅｍａｔｉｃｒｅｖｉｅｗｏｆｒａｎｄｏｍｉｚｅｄｃｏｎｔｒｏｌｌｅｄｔｒｉａｌｓ［Ｊ］．Ｉｎｆｌａｍｍ ＢｏｗｅｌＤｉｓ，２０１４，２０：５７６５８６． ３６ ＫａｎａｉＴ，ＭａｔｓｕｏｋａＫ，ＮａｇａｎｕｍａＭ，ｅｔａｌ．Ｄｉｅｔ，ｍｉｃｒｏｂｉｏｔａ， ａｎｄｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅ：ｌｅｓｓｏｎｓｆｒｏｍＪａｐａｎｅｓｅｆｏｏｄｓ ［Ｊ］．ＫｏｒｅａｎＪＩｎｔｅｒｎＭｅｄ，２０１４，２９：４０９４１５． ３７ ＵｒａｎｇａＪＡ，ＬóｐｅｚＭｉｒａｎｄａＶ，ＬｏｍｂóＦ，ｅｔａｌ．Ｆｏｏｄ，ｎｕｔｒｉｅｎｔｓ ａｎｄｎｕｔｒａｃｅｕｔｉｃａｌｓａｆｆｅｃｔｉｎｇｔｈｅｃｏｕｒｓｅｏｆｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌ ｄｉｓｅａｓｅ［Ｊ］．ＰｈａｒｍａｃｏｌＲｅｐ，２０１６，６８：８１６８２６． ３８ ＮｉｅｗｉａｄｏｍｓｋｉＯ，ＳｔｕｄｄＣ，ＷｉｌｓｏｎＪ，ｅｔａｌ．Ｉｎｆｌｕｅｎｃｅｏｆｆｏｏｄ ａｎｄｌｉｆｅｓｔｙｌｅｏｎｔｈｅｒｉｓｋ ｏｆｄｅｖｅｌｏｐｉｎｇｉｎｆｌａｍｍａｔｏｒｙ ｂｏｗｅｌ ｄｉｓｅａｓｅ［Ｊ］．ＩｎｔｅｒｎＭｅｄＪ，２０１６，４６：６６９６７６． ３９ ＤｕｒｃｈｓｃｈｅｉｎＦ，Ｐｅｔｒｉｔｓｃｈ Ｗ，ＨａｍｍｅｒＨＦ．Ｄｉｅｔｔｈｅｒａｐｙｆｏｒ ｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅｓ：Ｔｈｅｅｓｔａｂｌｉｓｈｅｄａｎｄｔｈｅｎｅｗ［Ｊ］． ＷｏｒｌｄＪＧａｓｔｒｏｅｎｔｅｒｏｌ，２０１６，２２：２１７９２１９４． ４０ ＨｏｕＪＫ，ＬｅｅＤ，ＬｅｗｉｓＪ．Ｄｉｅｔａｎｄｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅ： ｒｅｖｉｅｗ ｏｆ ｐａｔｉｅｎｔｔａｒｇｅｔｅｄ ｒｅｃｏｍｍｅｎｄａｔｉｏｎｓ ［Ｊ］． Ｃｌｉｎ ＧａｓｔｒｏｅｎｔｅｒｏｌＨｅｐａｔｏｌ，２０１４，１２：１５９２１６００． ４１ ＬｉＦ，ＬｉｕＸ，Ｗａｎｇ Ｗ，ｅｔａｌ．Ｃｏｎｓｕｍｐｔｉｏｎｏｆｖｅｇｅｔａｂｌｅｓａｎｄ ｆｒｕｉｔａｎｄｔｈｅｒｉｓｋｏｆｉｎｆｌａｍｍａｔｏｒｙｂｏｗｅｌｄｉｓｅａｓｅ：ａｍｅｔａａｎａｌｙｓｉｓ ［Ｊ］．ＥｕｒＪＧａｓｔｒｏｅｎｔｅｒｏｌＨｅｐａｔｏｌ，２０１５，２７：６２３６３０． （收稿日期：２０１７０６０３） （本文编辑：林磊） 国际消化病杂志２０１７年１２月第３７卷第６期 ＩｎｔＪＤｉｇＤｉｓ，Ｄｅｃｅｍｂｅｒ２５，２０１７，Ｖｏｌ．３７，Ｎｏ．６ ·３４７·