ABOUT THE AUTHORS JEREMY M.BERG received his B.S.and M.S. Tymoczko received his B.A.from the University of degrees in Chemistry from Stanford(where he did Chicago in 1970 and his Ph.D.in Biochemistry from research with Keith Hodgson and Lubert Stryer)and the University of Chicago with Shutsung Liao at the his Ph.D.in Chemistry from Harvard with Richard Ben May Institute for Cancer Research.He then had Holm.He then completed a postdoctoral fellowship a postdoctoral position with Hewson Swift of the with Carl Pabo in Biophysics at Johns Hopkins Department of Biology at the University of Chicago. University School of Medicine.He was an Assistant The focus of his research has been on steroid Professor in the Department of Chemistry at Johns receptors,ribonucleoprotein particles,and Hopkins from 1986 to 1990.He then moved to Johns proteolytic processing enzymes. Hopkins University School of Medicine as Professor and Director of the Department of Biophysics and LUBERT STRYER is Winzer Professor of Cell Biophysical Chemistry,where he remained until 2003. Biology,Emeritus,in the School of Medicine and He then became Director of the National Institute of Professor of Neurobiology,Emeritus,at Stanford General Medical Sciences at the National Institutes University,where he has been on the faculty since of Health.He is an elected Fellow of the American 1976.He received his M.D.from Harvard Medical Association for the Advancement of Science and School.Professor Stryer has received many awards an elected member of the Institute of Medicine of for his research on the interplay of light and life, the National Academy of Sciences.He received the including the Eli Lilly Award for Fundamental American Chemical Society Award in Pure Chemistry Research in Biological Chemistry,the Distinguished (1994)and the Eli Lilly Award for Fundamental Inventors Award of the Intellectual Property Owners' Research in Biological Chemistry(1995),was named Association,and election to the National Academy of Maryland Outstanding Young Scientist of the Year Sciences and the American Philosophical Society.He (1995),received the Harrison Howe Award(1997), was awarded the National Medal of Science in 2006. the Distinguished Service Award from the Biophysical The publication of his first edition of Biochemistry in Society(2009),and the Howard K.Schachman 1975 transformed the teaching of biochemistry Public Service Award from the American Society for Biochemistry and Molecular Biology(2011).He also GREGORY J.GATTO,JR.,received his A.B.degree received numerous teaching awards,including the in Chemistry from Princeton University,where he W.Barry Wood Teaching Award(selected by medical worked with Martin F.Semmelhack and was awarded students),the Graduate Student Teaching Award,and the Everett S.Wallis Prize in Organic Chemistry.In the Professor's Teaching Award for the Preclinical 2003,he received his M.D.and Ph.D.degrees from the Sciences.He is coauthor,with Stephen J.Lippard,of Johns Hopkins University School of Medicine,where he the textbook Principles of Bioinorganic Chemistry. studied the structural biology of peroxisomal targeting signal recognition with Jeremy M.Berg and received the JOHN L.TYMOCZKO is Towsley Professor of Michael A.Shanoff Young Investigator Research Award. Biology at Carleton College,where he has taught He then completed a postdoctoral fellowship in 2006 since 1976.He currently teaches Biochemistry, with Christopher T.Walsh at Harvard Medical School, Biochemistry Laboratory,Oncogenes and the where he studied the biosynthesis of the macrolide Molecular Biology of Cancer,and Exercise immunosuppressants.He is currently an Investigator Biochemistry and coteaches an introductory course, in the Heart Failure Discovery Performance Unit at Energy Flow in Biological Systems.Professor GlaxoSmithKline Pharmaceuticals.i v JEREMY M. BERG received his B.S. and M.S. degrees in Chemistry from Stanford (where he did research with Keith Hodgson and Lubert Stryer) and his Ph.D. in Chemistry from Harvard with Richard Holm. He then completed a postdoctoral fellowship with Carl Pabo in Biophysics at Johns Hopkins University School of Medicine. He was an Assistant Professor in the Department of Chemistry at Johns Hopkins from 1986 to 1990. He then moved to Johns Hopkins University School of Medicine as Professor and Director of the Department of Biophysics and Biophysical Chemistry, where he remained until 2003. He then became Director of the National Institute of General Medical Sciences at the National Institutes of Health. He is an elected Fellow of the American Association for the Advancement of Science and an elected member of the Institute of Medicine of the National Academy of Sciences. He received the American Chemical Society Award in Pure Chemistry (1994) and the Eli Lilly Award for Fundamental Research in Biological Chemistry (1995), was named Maryland Outstanding Young Scientist of the Year (1995), received the Harrison Howe Award (1997), the Distinguished Service Award from the Biophysical Society (2009), and the Howard K. Schachman Public Service Award from the American Society for Biochemistry and Molecular Biology (2011). He also received numerous teaching awards, including the W. Barry Wood Teaching Award (selected by medical students), the Graduate Student Teaching Award, and the Professor’s Teaching Award for the Preclinical Sciences. He is coauthor, with Stephen J. Lippard, of the textbook Principles of Bioinorganic Chemistry. JOHN L. TYMOCZKO is Towsley Professor of Biology at Carleton College, where he has taught since 1976. He currently teaches Biochemistry, Biochemistry Laboratory, Oncogenes and the Molecular Biology of Cancer, and Exercise Biochemistry and coteaches an introductory course, Energy Flow in Biological Systems. Professor Tymoczko received his B.A. from the University of Chicago in 1970 and his Ph.D. in Biochemistry from the University of Chicago with Shutsung Liao at the Ben May Institute for Cancer Research. He then had a postdoctoral position with Hewson Swift of the Department of Biology at the University of Chicago. The focus of his research has been on steroid receptors, ribonucleoprotein particles, and proteolytic processing enzymes. LUBERT STRYER is Winzer Professor of Cell Biology, Emeritus, in the School of Medicine and Professor of Neurobiology, Emeritus, at Stanford University, where he has been on the faculty since 1976. He received his M.D. from Harvard Medical School. Professor Stryer has received many awards for his research on the interplay of light and life, including the Eli Lilly Award for Fundamental Research in Biological Chemistry, the Distinguished Inventors Award of the Intellectual Property Owners’ Association, and election to the National Academy of Sciences and the American Philosophical Society. He was awarded the National Medal of Science in 2006. The publication of his first edition of Biochemistry in 1975 transformed the teaching of biochemistry. GREGORY J. GATTO, JR., received his A.B. degree in Chemistry from Princeton University, where he worked with Martin F. Semmelhack and was awarded the Everett S. Wallis Prize in Organic Chemistry. In 2003, he received his M.D. and Ph.D. degrees from the Johns Hopkins University School of Medicine, where he studied the structural biology of peroxisomal targeting signal recognition with Jeremy M. Berg and received the Michael A. Shanoff Young Investigator Research Award. He then completed a postdoctoral fellowship in 2006 with Christopher T. Walsh at Harvard Medical School, where he studied the biosynthesis of the macrolide immunosuppressants. He is currently an Investigator in the Heart Failure Discovery Performance Unit at GlaxoSmithKline Pharmaceuticals. ABOUT THE AUTHORS