第八章多序列比对的实际应用 页码,4/ ame-UIA MEMLPNQTI YI NNLNEKI KKEELKKSLYAI FSOFGQI LDI VALKTLKMRGO ★大大★大大大大大大大大大大大 大大大大大 hum-UlA AFVI FKEVSSATNALRSMOGFPFYDKPMRI QYAKTDSDI I AKMKGTEVERDRKR-EKRKP mse-UlA AFVI FKEVTSATNALRSMOGFPFYDKPMRI QYAKTDSDI I AKMKGTYVERDRKR-EKRKP xI a-UIA AFVI FKETSSATNALRSMOGFPFYDKPMRI QYSKTDSDI I AKMKGTFVERDRKRQEKRKV dme-U1A AFVI EKEI GSASNALRTMQGFPFYDKPMQL AYSKSDSDI VAKI KGTEKERPKKVKPPKPA 大大大大大大大大大大大大大大大大大大大大大大大大 大大大大大大大大大大★大大 hum-UlA KSOETPATKKAVQGGGATPVVGAVOGPVPGMPPMTOAPRI MHHMPGQPPYMPPPGMI PPP mse-UlA KSOETPAAKKAVOGGAAAPVVGAVO-PVPGMPPMPOAPRI MHHMPGOPPYMPPPGMI PPP xI a-UIA KVPEVOGVKNAMPGAALLPGVPGOMAAMQDMPGMTOAPRMMH-MAGOAPYMHHJPGMPPP dme-U1A PGTDEKKDKKKK hum-UlA GLAPGQI PPGAMPPOQLMPGOMPPAOPLSENPPNHI LFLTNLPEETNELMLSMLFNOFPG mse-UlA GLAPGQI PPGAMPPOQLMPGQMPPAOPLSENPPNHI LELTNLPEETNELMLSMLFNOFPG xI a-UlA GMAPGOMPPGGMPHGOLMPGOMAPMOPI SENPPNHI LFLTNLPEETNELMLSMLFNOFPG dme-UlA SSAENSNP------ NAQTEOPPNQI LFLTNLPEETNEMMLSMLFNOFPG hum-UlA FKEVRLVPGRHDI AFVEFDNEVOAGAARDALOGFKI TONNAMKI SFAKK mse-U1A FKEVRLVPGRHDI AFVEFDNEVOAGAARDALOGFKI TONNAMKI SFAKK xI a-UlA FKEVRLVPGRHDI AFVEFDNEVOAGAARESLOGFKI TOSNSMKI SFAKK dme-U1A FKEVRLVPNRHDI AFVEFTTELOSNAAKEALOGFKI TPTHAMKITFAKK 大大大大大大大 图8.1、以四种U1A序列为一系列的输入序列,使用 CLUSTAL W多序列比对程序后得到的比 对结果。保守性极高的残基位置由星号标记在序列下方的相应位置,保守性稍低的残基由打 点标记出来。 Mul talin file://E:wcb生物信息学(中译本)\第八章多序列比对的实际应用.htm 2005-1-18dme-U1A ---------MEMLPNQTIYINNLNEKIKKEELKKSLYAIFSQFGQILDIVALKTLKMRGQ * * *************.****************** . . .***** hum-U1A AFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKR-EKRKP mse-U1A AFVIFKEVTSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTYVERDRKR-EKRKP xla-U1A AFVIFKETSSATNALRSMQGFPFYDKPMRIQYSKTDSDIIAKMKGTFVERDRKRQEKRKV dme-U1A AFVIFKEIGSASNALRTMQGFPFYDKPMQIAYSKSDSDIVAKIKGTFKERPKKVKPPKPA ******* **.****.***********.* *.*.****.**.***. ** .* . hum-U1A KSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPP mse-U1A KSQETPAAKKAVQGGAAAPVVGAVQ-PVPGMPPMPQAPRIMHHMPGQPPYMPPPGMIPPP xla-U1A KVPEVQGVKNAMPGAALLPGVPGQMAAMQDMPGMTQAPRMMH-MAGQAPYMHHJPGMPPP dme-U1A PGTDEKKDKKKK-----------------------------------------------P . * * hum-U1A GLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPG mse-U1A GLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILELTNLPEETNELMLSMLFNQFPG xla-U1A GMAPGQMPPGGMPHGQLMPGQMAPMQPISENPPNHILFLTNLPEETNELMLSMLFNQFPG dme-U1A SSAENSNP-----------------NAQTEQPPNQILFLTNLPEETNEMMLSMLFNQFPG * . * . .*.***.*************.*********** hum-U1A FKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK mse-U1A FKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK xla-U1A FKEVRLVPGRHDIAFVEFDNEVQAGAARESLQGFKITQSNSMKISFAKK dme-U1A FKEVRLVPNRHDIAFVEFTTELQSNAAKEALQGFKITPTHAMKITFAKK ********.********* .*.*..**...******* ..***.**** ೒8.1ǃҹಯ⾡ U1A ᑣ߫Ўϔ㋏߫ⱘ䕧ܹᑣ߫ˈՓ⫼CLUSTAL W໮ᑣ߫↨ᇍ⿟ᑣৢᕫࠄⱘ↨ ᇍ㒧ᵰDŽֱᅜᗻᵕ催ⱘ⅟෎ԡ㕂⬅᯳োᷛ䆄೼ᑣ߫ϟᮍⱘⳌᑨԡ㕂ˈֱᅜᗻ⿡Ԣⱘ⅟෎⬅ᠧ ⚍ᷛ䆄ߎᴹDŽ MultiAlin ㄀ܿゴ໮ᑣ߫↨ᇍⱘᅲ䰙ᑨ⫼ 义ⷕˈ4/11 file://E:\wcb\⫳⠽ֵᙃᄺ˄Ё䆥ᴀ˅?㄀ܿゴ໮ᑣ߫↨ᇍⱘᅲ䰙ᑨ⫼.htm 2005-1-18 Click to buy NOW! PDF-XCHANGE www.docu-track.com Click to buy NOW! PDF-XCHANGE www.docu-track.com