nces in the H spectrum at-6 ppm (H1'H5)and 12 ppm (indole groups) 载 Crystal structure RNA contacts Cross-saturation Chemical shift perturbation Ramos et al(2000)JACS12211311-11314 Distance InformationRamos et al (2000) JACS 122 11311-11314 Nucleic acids have resonances in the 1H spectrum at ~6 ppm (H1’,H5) and 12 ppm (indole groups) Many proteins do not. Crystal structure RNA contacts Cross-saturation Chemical shift perturbation Distance Information