4. HIv protease and reverse transcriptase inhibitors for the treatment of hiv infections have changed a disease with a fatal prognosis to a potentially chronic one 5. Cancer is also being viewed as a potentially chronic. rather than fatal disease with newer non cytotoxic approaches Notes: H/, Human immunodeficiency virus• 4. HIV protease and reverse transcriptase inhibitors for the treatment of HIV infections have changed a disease with a fatal prognosis to a potentially chronic one. • 5. Cancer is also being viewed as a potentially chronic, rather than fatal disease with newer, noncytotoxic approaches. • Notes: HIV, Human immunodeficiency virus