Section 1 Origins of Medicinal Chemistry 1. Early investigations of natural products 1.1. In the so-called pre-scientific era Natural products having a history as folk remedies were in use. Fore examples, opium belladonna, cinchona bark, etc. Many drugs originally used as folk remedies, nowadays have been abandonedSection 1 Origins of Medicinal Chemistry 1. Early investigations of natural products • 1.1.In the so-called pre-scientific era • Natural products having a history as folk remedies were in use. Fore examples, opium, belladonna, cinchona bark, etc. Many drugs originally used as folk remedies, nowadays, have been abandoned