Outline ADME factors Review of Basic Pharmacokinetic Parameters Mathematical Basis of Clinical Pharmacokinetics Applications of Clinical Pharmacokinetics Factors affecting selection of the drug Clinical Pharmacokinetics in Drug Development Study questions 4Outline ADME factors Review of Basic Pharmacokinetic Parameters Mathematical Basis of Clinical Pharmacokinetics 4 Applications of Clinical Pharmacokinetics Study questions • Factors affecting selection of the drug • Clinical Pharmacokinetics in Drug Development