喜树碱Camptothecin Protein Synthesis Inhibition 拓扑异构抑制剂—向药物 ☆ 44 Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins. Bioorganic & Medicinal Chemistry 2013, 21: 6920-6928. 喜 树 碱 Camptothecin Camptothecin 拓扑异构酶I抑制剂——靶向药物 O N H O OH N Trichostatin A Trichostatin A have proven useful in the exploration of HDAC function in gene regulation as well as differentiation processes. Reveromycin A O O OH COOH O O COOH HOOC H H O O O O H2N N S N Pateamine A Protein Synthesis Inhibition Myriaporone OH O OH O OH O OH OH OH OH O O O OH