Middle-East J.Sci.Res.,(6):514-519.2010 5.Faulkner,D.J,0000.Mari produets.Nature Produet Reports.19:1 17.Lombardo,D.and E.A.Dennis,1985.Cobra veno alida 6.Proksch.P.and W.E.G.Muller,2006.Frontiers in of phospholipase inhibitor.J.Biological Marine Biotechnology.Horizon Bioscience: emistry.260:7234.7240 Norfolk,U.K. 18.Hao,D.,LA.Hammond,S.G.Eckhardt,A.Patnaik 7.Proksch.P.and RA.Edrada Ebel,002.Drugs fron CH Takimoto,G.H.Schwantz,A.D.Goetz A.W Tolcher.HA. McCreery,K.Mamun gy and 125134 I an 8.Carte,B.K.0000.Biomedical Potential of Marine Natural Products.Biosciences,pp:271-286. 9.Newmanm.D.J.and Cragg.2004.In Drug Discovery. 19 Man Cuevas Preventive Medicine. R.Garcia-Nieto. E.Marco and F.Gago. 2001 Adva ces in the emain,(Eds.)Humana Press Chemistry and Phammacology of Ecteinascidins.A Promising New Class of Anticancer Agents Current Medicinal Chemistry-Anti-Cancer Agents. GK.Schulte.1991.Dis polyhydroxylated lactone from the marine sponge :25 276. oluta lerratum to document cited ir 20.Smith and J.M.O. Femandes 2009.Nam mmia dis nnate systen CA 1139):75187b].J.Organic Chemistry,56:1346 11.Nieman A..JE Coleman,D Wallace,E.Pie Eds Science Publisher m, erge Enfield NH USA 1-241-275 Nature 21.Laz vici P N Primor and I M Loe 1986 Analogues 66183.109 Purification and pore-forming activity of two 12.Talpir,R..Y.Benayahu,Y.Kashman and L.Pannell polypeptides from the secretion of the Red Sea Schlever.1994.Hemiasterlin and geodiamolide TA. Moses sole (Pardachirus marmoratus)J.Biological ●hem1sry,26:1670416713 two new cytotoxic peptides from the marine sponge 453-445 minor (Kirkpatrick).Tetrahedron Letter 22.Thompson,S.A. Tachibana, K.Nakanishi 198 13 Cole defense RJ.Andersen Allen.1995.Cytotoxic p tides from the marine sponge Cymbastela sp.Tetrahedron 233.341.243 Letter.51:10653-10662 23.Oren,Z.and Y.Shai,1996.A class of highly 14.Towle M.J K.A.Salvato,J.Budrow,B.F.Wels, antibacterial peptides derived from pardaxin a pore forming peptide isolated from Moses sole fish Zhen MH Pardachirus Euroupean D Biochemistry.237:303-310. D A O 24.Cole. A nd P 1997. Diamond B A Littlefield 2001 In vitro and In vivo pleuro Anticancer Activities of Synthetic Macrocyclic Ketone Analogues of Halichondrin B Cancer Res. 1.1g.12013 1:1013-102 15 25.Sakai.R..KL Rinehart.V.Kishore.B.Kundu G Faireloth IB Gloer IR Camney M Manikoshi F.Sun,R.G.Hughes,J.R.D.Garcia-Gravalos Garcia de Quesada,G.R.Wilson and A Takai and N RM.Heid 199.Structure-Activity Relationships Fusetani,2002.Insight into Binding of Calyculin A of the Didemnins.J.Medicinal Chemistry, to Protein Phosphatase.Chemical Biol..9:309-319 39.28192834 518