4.教学方法 (1)Teaching method:Relevant concepts and theoretical framework,combined with typical drug examples. (2)Discussion method:Flipped classroom was encouraged. 5.教学评价 Take quick summary test,discuss with selected learning questions and frequently asked questions. Biopharmaceutic Considerations in Drug Product Des ign and In Vitro Drug Product Performance 1.教学目标 (1)Describe the biopharmaceuticfactors affecting drug design. (2)Differentiate between the termssolubility and dissolution,drug absorption andbioavailability, (3)Describe the various in vitro andin vivo tests commonly used toevaluate drug products. (4)Define in vitro-in vivo correlation(IVIVC)and explain why aLevel A correlation is the mostimportant correlation for IVIVC (5)Explain the biopharmaceuticclassification system andhow solubility,dissolution,and permeation apply to BCSclassification. 2.教学重难点 Understanding the biopharmaceuticfactors affecting drug design,the significance and method to estimate in vitro-in vivo correlation(IVIVC),the biopharmaceuticclassification system andhow solubility, dissolution,and permeation apply to BCSclassification. 3.教学内容4.教学方法 (1) Teaching method: Relevant concepts and theoretical framework, combined with typical drug examples. (2) Discussion method: Flipped classroom was encouraged. 5.教学评价 Take quick summary test, discuss with selected learning questions and frequently asked questions. 第十三章 Biopharmaceutic Considerations in Drug Product Design and In Vitro Drug Product Performance 1.教学目标 (1) Describe the biopharmaceuticfactors affecting drug design. (2) Differentiate between the termssolubility and dissolution, drug absorption andbioavailability, (3) Describe the various in vitro andin vivo tests commonly used toevaluate drug products. (4) Define in vitro–in vivo correlation(IVIVC) and explain why aLevel A correlation is the mostimportant correlation for IVIVC (5) Explain the biopharmaceuticclassification system andhow solubility, dissolution,and permeation apply to BCSclassification. 2.教学重难点 Understanding the biopharmaceuticfactors affecting drug design, the significance and method to estimate in vitro–in vivo correlation(IVIVC),the biopharmaceuticclassification system andhow solubility, dissolution,and permeation apply to BCSclassification. 3.教学内容