Pathophysiology Insufficient insulin secretion Decrease in glucose utilization Decreased metabolic synthesis Insufficient energy hyperglycemia Polyphagia Glucosuria -+Osmotic diuresis polyuria Emaciation Chronic dehydration Thirst and polydipsiaPathophysiology Insufficient insulin secretion Decrease in glucose utilization Decreased metabolic synthesis Insufficient energy hyperglycemia Polyphagia Glucosuria Osmotic diuresis Polyuria Emaciation Chronic dehydration Thirst and Polydipsia