Primary complement deficiencies 1)Components of activation pathways C1q,C1r,C1s,C4,C2,C3,MBL,D,B,C5,C6,C7,C8,C9 2)Control proteins soluble control proteins C1 inhibitor,factor I,factor H,C4b binding protein,S protein, SP-40,40 membrane regulatory proteins CD 55(DAF),MCP CD 46,CD 59,HRF/C8bp 3)Receptors for complement C1q receptor,CR1(CD 35),CR2(CD21),CR3(CD11b/CD18),CR4 (CD11c-CD18)Primary complement deficiencies 1) Components of activation pathways C1q, C1r,C1s,C4,C2,C3, MBL, D,B,C5,C6,C7,C8,C9 2) Control proteins • soluble control proteins C1 inhibitor, factor I, factor H,C4b binding protein,S protein, SP-40,40 • membrane regulatory proteins CD 55(DAF), MCP CD 46, CD 59, HRF/C8bp 3) Receptors for complement C1q receptor, CR1(CD 35), CR2 (CD21), CR3 (CD11b/CD18), CR4 (CD11c-CD18)