Eab Clobazam Drug-drug interactions 00 Weak cyp3A4 inducer- hormonal contraceptives CYP2D5 inhibitor o000oc0= CYP2C19 inhibitors may increase clobazam (fluconazole, fluvoxamine, ticlopide omeprazole Development of tolerance KENTUCKY College of PharmacyClobazam • Drug-drug interactions – Weak CYP3A4 inducer – hormonal contraceptives – CYP2D5 inhibitor – CYP2C19 inhibitors may increase clobazam (fluconazole, fluvoxamine, ticlopide, omeprazole) • Development of tolerance