(CH2)3N(CH3)2 2、吩噻嗪类药物的体内代谢 8-OH-CPZ 3-OH-CPZ (CH2)3N(CH3)2 7-OH-2-C吩噻嗪 CH3 —(CH2)3N —(CH2)3NH2 H (CH2)3N(CH3)2 单脱甲基氯丙嗪 双脱甲基氯丙嗪 CCI (CH2)3COOH HOSO3 HO 活性代谢物 CI (CH2)3N(CH3)2 (CH2)3N(CH3)2 Gluo (CH2)3N(CH3)2 (CH2)3N(CH3)2 10 10 2、吩噻嗪类药物的体内代谢 N S Cl (CH2)3N(CH3)2 O O N S Cl (CH2)3N(CH3)2 O N S Cl (CH2)3N(CH3)2 (CH2)3N CH3 H (CH2)3NH2 N S Cl (CH2)3N(CH3)2 HO N S Cl (CH2)3N(CH3)2 GluO 8-OH-CPZ 3-OH-CPZ N S Cl H 7-OH-2-Cl-吩噻嗪 N S Cl (CH2)3COOH N S Cl (CH2)3N(CH3)2 HOSO3 N S Cl (CH2)3N(CH3)2 H3CO 单脱甲基氯丙嗪 双脱甲基氯丙嗪 活性代谢物