武汉大学生命科学学院 2003-2004学年第一学期期末考试 《分子生物学》试卷 Final exam of molecular Biology Course(spring 2004) 年级 专业 学号 姓名 成绩 PART I: DESCRIPTION (2 points each) Your answer should describe what each item is and how it functions in the cell. Diagrams, structure and sequence information should be included in your answer, as necessary 1. Yeast artificial chromosome 2. RNA interference 3. Proteomics 4. Shine-Dalgarno sequence 5. Alternative splicing 6. Ribozyme 7. p-dependent termination 8. RNA ed iting 9. DNA lesions 10. Protein targeting PARTI: MULTIPLE CHOICES (I points each) Select the one best answer for each question 1. The catalytic activity for peptide bond formation(the peptidyl transferase activity)is located in the 1) RN of the large ribosomal subunit 2) leader sequence of the messenger RNA 3) RNA of the small ribosomal subun 4) proteins of the small ribosomal subunit 5) proteins of the large ribosomal subunit 2. Bidirectional and semi-conservative are two terms that refer to 1) transcription 2) translation 3) replication 4) all of the ab ove 3. The fact that most amino acids are specified by multiple codons is known as 2) the universality of the genetic code 3 codon bia 4) the anticodon hypothesis 5)the redundancy of the genetic code 4. RNa polymerase I is the eukaryotic enzyme responsible for:武汉大学生命科学学院 2003－2004 学年第一学期期末考试 《分子生物学》试卷 Final exam of Molecular Biology Course (Spring 2004) 年级______ 专业________ 学号_________ 姓名_______成绩______ PART I: DESCRIPTION (2 points each) Your answer should describe what each item is and how it functions in the cell. Diagrams, structure and sequence information should be included in your answer, as necessary. 1. Yeast artificial chromosome 2. RNA interference 3. Proteomics 4. Shine-Dalgarno sequence 5. Alternative splicing 6. Ribozyme 7. -dependent termination 8. RNA editing 9. DNA lesions 10. Protein targeting PART II: MULTIPLE CHOICES (1 points each) Select the one best answer for each question. 1. The catalytic activity for peptide bond formation (the peptidyl transferase activity) is located in the: 1) RNA of the large ribosomal subunit. 2) leader sequence of the messenger RNA. 3) RNA of the small ribosomal subunit. 4) proteins of the small ribosomal subunit. 5) proteins of the large ribosomal subunit. 2. Bidirectional and semi-conservative are two terms that refer to: 1) transcription. 2) translation. 3) replication. 4) all of the above. 5) none of the above. 3. The fact that most amino acids are specified by multiple codons is known as: 1) the “wobble” phenomenon. 2) the universality of the genetic code. 3) codon bias. 4) the anticodon hypothesis. 5) the redundancy of the genetic code. 4. RNA polymerase I is the eukaryotic enzyme responsible for: