Transmission L, interrogans propagates in the kidney of infected patients or animals and can be shed in the urine. Animal urine from infected rodents infected farm animals(usually inapparent infection) Contaminate soil and water Enters body, through healthy or broken skin. Human leptospirosis, L, interrogans rapidly enters bloodstream to cause leptospiremia18 • L. interrogans propagates in the kidney of infected patients or animals and can be shed in the urine. • Animal urine from infected rodents, infected farm animals (usually inapparent infection) • Contaminate soil and water • Enters body through healthy or broken skin. • Human leptospirosis. L. interrogans rapidly enters bloodstream to cause leptospiremia Transmission