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Surfctant Phase Behavior micelle hexagoral reverse hexagunal reverse micelle Commercial liposome/lipid complex-based products US-FDA approved for human use(injectable drugs) Product Route of injection Drug Particle type Approved Indication Ambisome i.v. Amphotericin B Liposome (chemotherapy) (LUV) Severe fungal infections Abelcet iv. Amphotericin B Lipid complex (chemotherapy) (ribbons) Severe fungal infections Amphotec iv. Amphotericin B Lipid complex (chemotherapy) (disc) Severe fungal infections DaunoXome iv Daunorubicin Liposome (chemotherapy) (LUV) Blood tumors Doxil iv. Doxorubicin PEGylated(sterically stabilized)SUV-LUV Kaposi's sarcoma (chemotherapy) liposome Ovarian/Breast cancer Visudyne* iv. Benzoprophyrin Liposomes Age-related molecular degeneration(AMD) Multivesicular large Lymphomatos Depocyt Spinal Cytarabine liposomes meningitis (late stage lymphoma) 12-23um DepoDur Epidural Morphine sulfate Multivesicular Pain management liposomes5 Commercial liposome/lipid complex-based products US-FDA approved for human use (injectable drugs) Product Route of injection Ambisome i.v. i.v. i.v. i.v. i.v. i.v. Depocyt Spinal Cytarabine Multivesicular large liposomes Lymphomatos meningitis (late stage lymphoma) DepoDur Epidural Morphine sulfate 12-23 μm Multivesicular liposomes Amphotericin B (chemotherapy) Liposome (LUV) Severe fungal infections Pain management Abelcet Amphotericin B (chemotherapy) Lipid complex (ribbons) Severe fungal infections Amphotec Amphotericin B (chemotherapy) Lipid complex (disc) Severe fungal infections DaunoXome Daunorubicin (chemotherapy) Liposome (LUV) Blood tumors Doxil Doxorubicin (chemotherapy) PEGylated (sterically stabilized) SUV-LUV liposome Kaposi’s sarcoma Ovarian/Breast cancer Visudyne* Benzoprophyrin Liposomes Age-related molecular degeneration (AMD) Drug Particle type Approved Indication
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