Section 2:Diuretics hydrochlorothiazide Mechanism of Action in Heart Failure Preload reduction:reduction of excess plasma volume and edema fluid o Afterload reduction:lowered blood pressureSection 2: Section 2: Diuretics Diuretics  Preload reduction: reduction of excess plasma volume and edema fluid  Afterload reduction: lowered blood pressure Mechanism of Action in Heart Failure Mechanism of Action in Heart Failure hydrochlorothiazide