Streptococcus Pyogenes Pathogenesis Serious infection of Beta-hemolytic group A s pyogenes can results in bacteremia with sepsis, which is rapidly fatal Usually involve rapidly spreading infection along lymphatics with little focal suppuration From lymphatics infection can spread via blood streamStreptococcus Pyogenes Pathogenesis • Serious infection of Beta-hemolytic group A S.pyogenes can results in bacteremia with sepsis, which is rapidly fatal • Usually involve rapidly spreading infection along lymphatics with little focal suppuration. • From lymphatics infection can spread via blood stream