Unit7:系统综述与meta分析 主讲教师：张博恒 助理教师：施鹕 一、教学目的 掌握和熟悉系统综述和Mta分析的基本原理和方法 二、教学内容 1.了解系统综述与meta分析的概念 2.掌握系统综述的评价方法和meta分析结果的解释 3.了解系统综述的实施步骤 三、教学重点系统综述的评价方法与meta分析结果的解释 四、教学难，点critical appraisal of a systematic review 五、中文和英文关健词 系统综述systematic review meta分析meta-analysis PICO Population,Intervention,Comparison,Outcome 文献评阅 critical appraisal 异质性 heterogeneity 六、预习与课堂讨论 1.预习并思考 Scenario Your team is having a discussion about the methods for cardiopulmonary resuscitation for cardiac arrests.Someone suggests that the evidence now favours chest-compression only methods as opposed to standard CPR(chest compressior and ventilation),but someone else says that only applies to out of hospital arrests Your team wonders what they should use themselves and what they should teach lay people. Questions (1)What is your clinical question(PICO)? (2)What sort of evidence would be helpful to answer the question? 3)Where would you search for evidence and what terms would you use? (4)Read the systematic review:Chest-compression-only versus standard cardiopulmonary resuscitation:a meta-analysis by Hipfl M..Selig H.F.. Nagele p.How does their search compare to vours? further reading (1)Hupfl M..Selig H.F,Nagele P.,Chest-compression-only versus standard cardiopulmonary resuscitation:a meta-analysis.Lancet,2010:376:1552-57. (2)Akobeng AK.Understanding systematic reviews and meta-analysis.Arch Dis Child,.2005,90:845-848.Unit 7：系统综述与 meta 分析 主讲教师：张博恒 助理教师：施鹏 一、教学目的 掌握和熟悉系统综述和 Meta 分析的基本原理和方法 二、教学内容 1. 了解系统综述与 meta 分析的概念 2. 掌握系统综述的评价方法和 meta 分析结果的解释 3. 了解系统综述的实施步骤 三、教学重点 系统综述的评价方法与 meta 分析结果的解释 四、教学难点 critical appraisal of a systematic review 五、中文和英文关键词 系统综述 systematic review meta 分析 meta-analysis PICO Population, Intervention, Comparison, Outcome 文献评阅 critical appraisal 异质性 heterogeneity 六、预习与课堂讨论 1. 预习并思考 Scenario Your team is having a discussion about the methods for cardiopulmonary resuscitation for cardiac arrests. Someone suggests that the evidence now favours chest-compression only methods as opposed to standard CPR (chest compression and ventilation), but someone else says that only applies to out of hospital arrests. Your team wonders what they should use themselves and what they should teach lay people. Questions (1) What is your clinical question (PICO)? (2) What sort of evidence would be helpful to answer the question? (3) Where would you search for evidence and what terms would you use? (4) Read the systematic review: Chest-compression-only versus standard cardiopulmonary resuscitation: a meta-analysis by Hűpfl M., Selig H.F., Nagele P. How does their search compare to yours? Further reading (1) Hűpfl M., Selig H.F., Nagele P., Chest-compression-only versus standard cardiopulmonary resuscitation: a meta-analysis. Lancet, 2010;376:1552-57. (2) Akobeng AK. Understanding systematic reviews and meta-analysis. Arch Dis Child,2005;90:845-848